45673
Fluka
Erythromycin
BioChemika, ≥95.0% (NT)
| CAS Number: | 114-07-8 |
| Linear Formula: | C37H67NO13 |
| Molecular Weight: | 733.93 |
| Beilstein Registry Number: | 75279 |
| EC Number: | 204-040-1 |
| MDL number: | MFCD00084654 |
| PubChem Substance ID: | 24869225 |
Description
| Biochem/physiol Actions | Mode of Action: Inhibits elongation at transpeptidation step. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria. |
| Other Notes | Macrolide antibiotic. |
| Inhibits bacterial protein synthesis by binding to the ribosomes1; Inducible erythromycin resistance in bacteria2 |
Properties
| product line | BioChemika |
| assay | ≥95.0% (NT) |
| optical activity | [α]20/D −75±4°, c = 2% in ethanol |
| mp | 133-135 °C |
| Gene Information | human ... ABCB1(5243), CYP3A4(1576), MLNR(2862) |
| mouse ... Abcb1a(18671), Abcb1b(18669) |
Safety
| Personal Protective Equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
| WGK Germany | 2 |
| RTECS | KF4375000 |
References
| Cited Reference | 1. H. Teraoka Umsch. Wiss. Tech 77, 347, (1977) |
| 2. B. Weisblum Br. Med. Bull. 40, 47, (1984) Abstract | |
| Merck | Merck 13,3714 |
| Beilstein | Beil. 18,V,10,398 |
